منابع مشابه
Meropenem-induced low valproate levels in a cerebral palsy child.
Valproate (VPA) is commonly prescribed as first-line agent to control seizure disorders.1 Concomitant use of cytochrome P450 (CYP) inducers or inhibitors can result in altered VPA absorption or elimination rates. While CYP-based drug interactions are well described, non-CYP interactions are increasingly becoming visible in literature. The importance of non-CYP interaction is exemplified by a ca...
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A 34 day-old girl infant was admitted for poor feeding and cholestasis. She had a bulging fontanelle, with no evidence of intracranial infection or hemorrhage. Investigations demonstrated that she had galactosemia. Computed tomographic scans demonstrated the presence of diffuse cerebral edema. After treatment the edema resolved.
متن کاملValproate Induced Hypertensive Urgency
Valproate is a medication used in the treatment of seizures, bipolar disorder, migraines, and behavioral problems. Here we present a case of an 8-year-old boy who presented with hypertensive urgency after initiation of valproate. Primary treatment of his hypertension was ineffective. Blood pressure stabilization was achieved following discontinuation of valproate. Clinicians should be aware of ...
متن کاملAttenuation of thrombin-induced brain edema by cerebral thrombin preconditioning.
BACKGROUND AND PURPOSE Edema formation after intracerebral hemorrhage has been linked to thrombin toxicity induced by the clot. However, thrombin at low concentrations actually protects neurons and astrocytes in culture from hypoglycemic and ischemic cell death. It is also known that a brief episode of brain ischemia increases neuronal tolerance to a subsequent severe ischemic episode. The obje...
متن کاملHigh altitude cerebral edema.
This review focuses on the epidemiology, clinical description, pathophysiology, treatment, and prevention of high altitude cerebral edema (HACE). HACE is an uncommon and sometimes fatal complication of traveling too high, too fast to high altitudes. HACE is distinguished by disturbances of consciousness that may progress to deep coma, psychiatric changes of varying degree, confusion, and ataxia...
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ژورنال
عنوان ژورنال: Pediatric Neurology Briefs
سال: 1992
ISSN: 2166-6482,1043-3155
DOI: 10.15844/pedneurbriefs-6-9-10